2024 (#co-first, *corresponding author):

Xu Y#, Li Y#, Hu H, Jiao H, and Zhao H* (2024). Genomic and functional insights into dietary diversification in New World leaf-nosed bats (Phyllostomidae). Journal of Systematics and Evolution. In press.


Li Y#, Jiao H#, Sin SYW, Wang R, Rossiter SJ, and Zhao H* (2023). Common ancestors of bats were omnivorous suggested by resurrection of ancestral sweet receptors. Science Bulletin. 68(16):1748-1751. PDF  Link  News-1 News-2

Tian S#, Zeng J#, Jiao H, Zhang D, Zhang L, Lei CQ, Rossiter SJ, and Zhao H* (2023). Comparative analyses of bat genomes identify distinct evolution of immunity in Old World fruit bats. Science Advances. 9(18):eadd0141. PDF  Link  News

Hao X, Lu Q*, and Zhao H* (2023). A molecular phylogeny for all 21 families within Chiroptera (bats). Integrative Zoology. PDF Link Graphic_Abstract

Hao X, Jiao H, Zou D, Li Q, Yuan X, Liao W, Jiang P, and Zhao H* (2023). Evolution of bitter receptor genes and ontogenetic dietary shift in a frog. PNAS. 120(8):e2218183120. PDF Link  Highlighted in this issue Commentary

Poon ESK, Chen G, Tsang HY, Shek CT, Tsui WC, Zhao H, Guénard B, and Sin SYW (2023). Species richness of bat flies and their associations with host bats in a subtropical East Asian region. Parasites & Vectors. 16:37. PDF Link


Wang Y#, Wang C#, Hong W, Tian S, Lu Q, Wang BJ, Jin H, Zhuoma N, Lu X, and Zhao H* (2022). Genomic analysis of Tibetan ground tits identifies molecular adaptations associated with cooperative breeding. Current Zoology. PDF.  Link

Xiong Q#, Cao L#, Ma C#, Tortorici MA#, Liu C, Si J, Liu P, Gu M, Walls AC, Wang C, Shi L, Tong F, Huang M, Li J, Zhao C, Shen C, Chen Y, Zhao H, Lan K, Corti D, Veesler D*, Wang X*, and Yan H* (2022). Close relatives of MERS-CoV in bats use ACE2 as their functional receptors. Nature. PDF. Link

Wu J#, Zhang L#, Shen C, Sin SYW, Lei C, and Zhao H* (2022). Comparative transcriptome analysis reveals molecular adaptations underlying distinct immunity and inverted resting posture in bats. Integrative Zoology. PDF. Link


Jiao H#, Xie HW#, Zhang L#, Zhuoma N, Jiang P, and Zhao H* (2021). Loss of sweet taste despite the conservation of sweet receptor genes in insectivorous bats. PNAS. 118(4):e2021516118. PDF Link 科学网 中国科学报 NewScientist News-PDF

Yan H#, Jiao H#, Liu Q, Zhang Z, Xiong Q, Wang BJ, Wang X, Guo M, Wang LF, Lan K*, Chen Y*, and Zhao H* (2021). ACE2 receptor usage reveals variation in susceptibility to SARS-CoV and SARS-CoV-2 infection among bat species. Nature Ecology & Evolution. 5(5):600-608. PDF  Link

Zou D, Tian S, Zhang T, Zhuoma N, Wu G, Wang M, Dong L, Rossiter SJ, and Zhao H* (2021). Vulture genomes reveal molecular adaptations underlying obligate scavenging and low levels of genetic diversity. Molecular Biology and Evolution. 38(9):3649-3663. PDF Link

Jiao H#, Wang Q#, Wang BJ, Li K, Lövy M, Nevo E, Li Q, Su W, Jiang P, and Zhao H* (2021). Local adaptation of bitter taste and ecological speciation in a wild mammal. Molecular Biology and Evolution. 38(10):4562-4572. PDF  DOI: 10.1093/molbev/msab205

Lu Q, Jiao H, Wang Y, Norbu N, and Zhao H* (2021). Molecular evolution and deorphanization of bitter taste receptors in a vampire bat. Integrative Zoology. 16(5):659-669. PDF 光明网 封面论文

Zhao H* (2021). Evolution of V1R repertoires in subterranean rodents. Encyclopedia of Life Sciences. 2: 1-6. John Wiley & Sons, Chichester, UK. PDF (Invited Review) DOI: 10.1002/9780470015902.a0029079

Tan S, Zhou Y, Zhao H, Wu J, Yu H, Yang Y, Yang Y, Zhao H*, and Li H* (2021). Comprehensive transcriptome analysis of hypothalamus reveals genes  associated with disorders of sex development in pigs. Journal of Steroid Biochemistry and Molecular Biology. 210:105875. PDF

Santillan DM, Lama T, Guerrero YG, Brown A, Donat P, Zhao H, Rossiter SJ, Yohe L, Potter J, Teeling E, Vernes S, Davies K, Myers E, Hughes G, Huang Z, Hoffmann FG, Corthals A, Ray D*, and Davalos L* (2021). Large-scale genome sampling reveals unique immunity and metabolic adaptations in bats. Molecular Ecology. PDF.  DOI: 10.1111/mec.16027

张语之#,李远球#,何向阳,彭兴文,王健,李玉龙,王俊华,谢焕旺,郭敏,赵华斌*,张礼标* (2021). 广东石门台国家级自然保护区蝙蝠多样性. 动物学杂志. 56(2):208-213. PDF


Wang K, Tian S, Galindo-González J, Dávalos LM, Zhang Y, and Zhao H* (2020). Molecular adaptation and convergent evolution of frugivory in Old World and neotropical fruit bats. Molecular Ecology. 29(22):4366-4381. PDF

Wang BJ, Xia JM, Wang Q, Yu JL, Song Z, and Zhao H* (2020). Diet and adaptive evolution of alanine-glyoxylate aminotransferase mitochondrial targeting in birds. Molecular Biology and Evolution. 37(3):786-798. PDF

Zhao H* (2020). COVID-19 drives new threat to bats in China. Science. 367(6485):1436. DOI: 10.1126/science.abb3088 PDF (Letter)

Tian S#, Zhou X#, Phuntsok T, Zhao N, Zhang D, Ning C, Li D*, and Zhao H* (2020). Genomic analyses reveal genetic adaptations to tropical climates in chickens. iScience. 23(11):101644. PDF

Yan H#, Jiao H#, Liu Q, Zhang Z, Wang X, Guo M, Wang BJ, Lan K*, Chen Y*, and Zhao H* (2020). Many bat species are not potential hosts of SARS-CoV and SARS-CoV-2: Evidence from ACE2 receptor usage. (bioRxiv) Preprint PDF doi:

Hong W#, Li K#, Sharaf K, Song X, Pavlìcek T, Zhao H*, and Nevo E* (2020).  Genome-wide analysis revisits incipient sympatric and allopatric speciation in a beetle.  Israel Journal of Ecology and Evolution. 67(1-2):69-80. PDF

Damas J, Hughes GM, Keough KC, Painter CA, Persky NS, Corbo M, Hiller M, Koepfli KP, Pfenning AR, Zhao H, Genereux DP, Swofford R, Pollard KS, Ryder OA, Nweeia MT, Lindblad-Toh K, Teeling EC, Karlsson EK, and Lewin HA* (2020).  Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates. PNAS. 117(36): 22311-22322. PDF

Zhou ZS, Li MX, Liu J, Jiao H, Xia JM, Shi XJ, Zhao H, Chu L, Liu J, Qi W, Luo J, and Song BL* (2020). Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2. Nature Communications. 11:379. PDF

曾嘉鸣,赵华斌* (2020). 蝙蝠抗病毒天然免疫的研究进展. 兽类学报. (Review) PDF

江廷磊,赵华斌,何彪,张礼标,罗金红,刘颖,孙克萍,余文华,吴毅,冯江* (2020). 中国蝙蝠研究进展、受胁状况及保护对策. 兽类学报. (Review) PDF


Jiao H#, Zhang L#, Xie HW, Simmons NB, Liu H, and Zhao H* (2019). Trehalase gene as a molecular signature of dietary diversification in mammals. Molecular Biology and Evolution.36(10):2171-2183. PDF  cover

Wang Y, Jiao H, Jiang P, and Zhao H* (2019). Functional divergence of bitter taste receptors in a nectar-feeding bird. Biology Letters. 15(9):20190461. PDF

Jiao H, Hong W, Nevo E, Li K, and Zhao H* (2019). Convergent reduction of V1R genes in subterranean rodents. BMC Evolutionary Biology. 19(1):176. PDF

Abduriyim S, Zou DH, and Zhao H* (2019). Origin and evolution of the major histocompatibility complex class I region in eutherian mammals. Ecology and Evolution. 9(13):7861-7874. PDF

Tang J, Zhang K, Dong J, Yan C, Hu C, Ji H, Chen L, Chen S, Zhao H, and Song Z* (2019). Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact. Cell Death & Differentiation. 27(1):146-160. PDF

Chen YH, and Zhao H* (2019). Evolution of digestive enzymes and dietary diversification in birds. PeerJ. 7:e6840. PDF

Wang Y, Zajac AL, Lei W, Christensen CM, Margolskee RF, Bouysset C, Golebiowski J, Zhao H, Fiorucci S, and Jiang P* (2019). Metal ions activate the human taste receptor TAS2R7. Chemical Senses. 44(5):339-347. PDF

Simões BF, Foley NM, Hughes GM, Zhao H, Zhang S, Rossiter SJ, Teeling EC* (2019). As blind as a bat? Opsin phylogenetics illuminates the evolution of color vision in bats. Molecular Biology and Evolution. 36(1):54-68. PDF

陈宇轩,赵华斌* (2019). 吸血蝙蝠食性特化及其研究现状. 兽类学报. 39(2):202-208. (Review) PDF


Jiao H, Wang Y, Zhang L, Jiang P*, and Zhao H* (2018). Lineage-specific duplication and adaptive evolution of bitter taste receptor genes in bats. Molecular Ecology. 27(22):4475-4488. PDF

Wu J#, Jiao H#, Simmons NB, Lu Q*, and Zhao H* (2018). Testing the sensory tradeoff hypothesis in New World bats. Proceedings of the Royal Society B: Biological Sciences. 285(1885):20181523. (Cover Story) PDF cover

Teeling EC*, Vernes SC, Davalos LM, Ray DA, Gilbert MTP, Myers E, and Bat1K consortium (Huabin Zhao as one member of Bat1K consortium) (2018). Bat biology, genome, and the Bat1K project: To generate chromosome-level genomes for all living bat species. Annual Review of Animal Biosciences. 6:23-46. (Review) PDF Bat1k consortium


Yang JR, Maclean CJ, Park C, Zhao H, Zhang J* (2017). Intra and interspecific variations of gene expression levels in yeast are largely neutral. Molecular Biology and Evolution. 34(9):2125-2139. PDF

Wang K, Hong W, Jiao H, and Zhao H* (2017). Transcriptome sequencing and phylogenetic analysis of four species of luminescent beetles. Scientific Reports. 7(1):1814. PDF

Zhang Y, Jiao Y, Jiao H, Zhao H*, and Zhu YX* (2017). Two-step functional innovation of the stem-cell factors wus/wox5 during plant evolution. Molecular Biology and Evolution. 34(3):640-653. PDF

Zhao JS, Wang AY, Zhao HB, Chen YH* (2017). Transcriptome sequencing and differential gene expression analysis of the schistosome-transmitting snail Oncomelania hupensis inhabiting hilly and marshland regions. Scientific Reports. 7:15809. PDF


Lu Q, Wang K, Lei F, Yu D, and Zhao H*(2016). Penguins reduced olfactory receptor genes common to other waterbirds. Scientific Reports. 6:31671. PDF


Li K#, Hong W#, Jiao H, Wang GD, Rodriguez KA, Buffenstein R, Zhao Y, Nevo E*, and Zhao H* (2015). Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax. PNAS. 112(38):11905-11910. PDF

Zhao H, Li J, and Zhang J* (2015). Molecular evidence for the loss of three basic tastes in penguins. Current Biology. 25(4):R141-R142. PDF  BBC  U-M News Science Daily

Wang K, and Zhao H* (2015). Birds generally carry a small repertoire of bitter taste receptor genes. Genome Biology and Evolution. 7(9):2705-2715. PDF

Di Z, Yu Y, Wu Y, Hao P, He Y, Zhao H, Li Y, Zhao G, Li X, Li W, Cao Z* (2015). Genome-wide analysis of homeobox genes from Mesobuthus martensii reveals Hox gene duplication in scorpions. Insect Biochemistry and Molecular Biology. 61:25-33. PDF

Feng P, Zhao H, Lu X* (2015). Evolution of mitochondrial DNA and its relation to basal metabolic rate. Mitochondrial DNA. 26(4):566-571. PDF

Jiao H, Ding M, Zhao H* (2015).  Sequence and organization of complete mitochondrial genome of the firefly, Aquatica leii (Coleoptera: Lampyridae). Mitochondrial DNA. 26(5):775-776. PDF

Wang K, Hao J, Zhao H* (2015). Characterization of complete mitochondrial genome of the skipper butterfly, Celaenorrhinus maculosus (Lepidoptera: Hesperiidae). Mitochondrial DNA. 26(5):690-691. PDF

敖亮,冯平,郑劲松,于黎,赵华斌* (2015). 海洋哺乳动物信息素嗅觉的分子进化. 中国科学. 45(2):175-182. PDF


Hong W, and Zhao H* (2014). Vampire bats exhibit evolutionary reduction of bitter taste receptor genes common to other bats. Proceedings of the Royal Society B: Biological Sciences. 281(1788): 20141079. PDF  National Geographic  TheScientist  FoxNews

Feng P#, Zheng J#, Rossiter SJ, Wang D, and Zhao H*(2014). Massive losses of taste receptor genes in toothed and baleen whales. Genome Biology and Evolution. 6(6):1254-1265. PDF

Science: Whales can't taste anything but salt [Link]

Genome Biol Evol Highlight [Link]

Dolphins and whales can only taste salty food [Video]

Lin GH, Wang K, Deng XG, Nevo E, Zhao F, Su JP, Guo SC, Zhang TZ*, and Zhao H* (2014).  Transcriptome sequencing and phylogenomic resolution within Spalacidae (Rodentia). BMC Genomics. 15:32. PDF


Feng P, and Zhao H* (2013). Complex evolutionary history of the vertebrate sweet/umami taste receptor genes. Chinese Science Bulletin. 58(18):2198-2204. PDF

He Y, Zhao R, Di Z, Li Z, Xu X, Hong W, Wu Y, Zhao H, Li W, Cao Z* (2013). Molecular diversity of Chaerilidae venom peptides reveals the dynamic evolution of scorpion venom components from Buthidae to non-Buthidae. Journal of Proteomics. 89:1-14. PDF


Zhao H*, and Zhang J* (2012). Mismatches between feeding ecology and taste receptor evolution: An inconvenient truth. PNAS. 109(23):E1464. (Letter to Editor) PDF

Zhao H, Xu D, Zhang S, Zhang J* (2012). Genomic and genetic evidence for the loss of umami taste in bats. Genome Biology and Evolution. 4(1):73-79. PDF

Hao J*, Sun Q, Zhao H, Sun X, Gai Y, Yang Q* (2012).  The complete mitochondrial genome of Ctenoptilum vasava (Lepidoptera: Hesperiidae: Pyrginae) and its phylogenetic implication. Comparative and Functional Genomics. 2012:328049. PDF


Zhao H, Xu D, Zhang S*, Zhang J* (2011). Widespread losses of vomeronasal signal transduction in bats. Molecular Biology and Evolution. 28(1):7-12. PDF


Zhao H, Yang JR, Xu H, Zhang J* (2010). Pseudogenization of the umami taste receptor gene Tas1r1 in the giant panda coincided with its dietary switch to bamboo. Molecular Biology and Evolution. 27(12):2669-2673. PDF

Zhao H, Zhou Y, Pinto CM, Charles-Dominique P, Galindo-González J, Zhang S*, Zhang J* (2010). Evolution of the sweet taste receptor gene Tas1r2 in bats. Molecular Biology and Evolution. 27(11):2642-2650. PDF


Zhao H, Rossiter SJ*, Teeling EC*, Li C, Cotton JA, Zhang S* (2009). The evolution of color vision in nocturnal mammals. PNAS. 106(22):8980-8985. PDF

Zhao H, Ru B, Teeling EC, Faulkes CG, Zhang S*, Rossiter SJ* (2009). Rhodopsin molecular evolution in mammals inhabiting low light environments. PLoS ONE. 4(12):e8326. PDF